Approach to the Control of Antimicrobial Resistance: Are We Missing the Plot?

The topic of antimicrobial resistance (AMR) has been the subject
of much discussion for several decades. The Centers for Disease
Control and Prevention (CDC) has put forth three broad steps to
deal with antibiotic resistance. This includes (a) detect, respond,
and contain resistant pathogens; (b) prevent spread of resistant
infections; and (c) encourage innovation for new strategies, drugs,
and diagnostics. Although globally AMR is on the increase, a
context-specific approach may be required given the geographic
variations in the extent and type of AMR. Thus, the approach to
AMR in a particular region would require (a) the assessment of the
magnitude of AMR in that region, (b) an understanding of the factors
that contribute to AMR, (c) outlining strategies to combat AMR, (d)
implementation of strategies, and (e) the evaluation of the success
of such strategies. Over two decades ago, an editorial suggested
that it was time for action to control AMR. The authors put forth
the argument that “although we still need a better understanding
of the factors involved in the emergence and spread of antibiotic
resistance, action cannot wait until all the answers are available”.